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The gene sequencing and analysis were done collaboratively by teams at Stanford, Johns Hopkins, and the Broad Institute of MIT and Harvard. By knowing the unique genetic and molecular signature of Jobs’s tumors, his doctors had been able to pick specific drugs that directly targeted the defective molecular pathways that caused his cancer cells to grow in an abnormal manner. This approach, known as molecular targeted therapy, was more effective than traditional chemotherapy, which attacks the process of division of all the body’s cells, cancerous or not. This targeted therapy was not a silver bullet, but at times it seemed close to one: It allowed his doctors to look at a large number of drugs—common and uncommon, already available or only in development—to see which three or four might work best. Whenever his cancer mutated and repaved around one of these drugs, the doctors had another drug lined up to go next.disinfectant spray kill fleasAt a meeting early in his tenure, Cook was told of a problem with one of Apple’s Chinese suppliers. “This is really bad,” he said. “Someone should be in China driving this.” Thirty minutes later he looked at an operations executive sitting at the table and unemotionally asked, “Why are you still here?” The executive stood up, drove directly to the San Francisco airport, and bought a ticket to China. He became one of Cook’s top deputies.n95 9210 mask smokeHer eyes opened with a slow languid movement and met mine, but their expression was so queer that I hastened to reassure her again.“Are they not pretty?” she said. “See, here is a falcon-gentil. We call it ‘ignoble,’ because it takes the quarry in direct chase. This is a blue falcon. In falconry we call it ‘noble’ because it rises over the quarry, and wheeling, drops upon it from above. This white bird is a gerfalcon from the north. It is also ‘noble!’ Here is a merlin, and this tiercelet is a falcon-heroner.”protective clothing meetsJobs’s compulsive search for self-awareness also led him to undergo primal scream therapy, which had recently been developed and popularized by a Los Angeles psychotherapist named Arthur Janov. It was based on the Freudian theory that psychological problems are caused by the repressed pains of childhood; Janov argued that they could be resolved by re-suffering these primal moments while fully expressing the pain—sometimes in screams. To Jobs, this seemed preferable to talk therapy because it involved intuitive feeling and emotional action rather than just rational analyzing. “This was not something to think about,” he later said. “This was something to do: to close your eyes, hold your breath, jump in, and come out the other end more insightful.”